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If additional validation of acetylcarnitine is carried out in a follow-up study, taking into account the larger sample size, controlled subject variables, antidepressant type, and heterogeneity due to pharmacomechanism, the potential of acetylcarnitine as a biomarker for diagnosing depression and remission status will be further elucidated

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The lower overall cancer risks observed in the tirzepatide 10 mg arm compared to the placebo arm may be due to chance

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