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Pro-inflammatory factors such as IFN- weaken GSH synthesis by downregulating the cystine transporter SLC7A11, thereby enhancing ferroptosis sensitivity (Wang et al., 2020) (209)
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Perfusion was performed by flushing pre-warmed RPMI containing phenol red and L-glutamine through a 25- and 3/8-gauge needle placed into the aorta attached to Tygon tubing aided by the Masterflex L/S perfusion pump as described 81
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