You should contact your GP or seek specialist referral if you are experiencing: Unexplained weight gain or difficulty losing weight despite lifestyle changes Symptoms that may suggest growth hormone deficiency , such as persistent fatigue, reduced muscle mass, increased abdominal fat, or low mood formal biochemical testing is required before any treatment is initiated Poorly controlled blood glucose or a new diagnosis of type 2 diabetes Interest in weight-management medicines , to discuss licensed options available through NHS or regulated private pathways access to weight-management pharmacotherapy on the NHS is typically via specialist weight management services, subject to local eligibility criteria Seek urgent medical attention via NHS 111 or, if necessary, 999 if you experience severe or persistent abdominal pain (which may indicate pancreatitis), signs of a serious allergic reaction, chest pain or palpitations, or symptoms of diabetic ketoacidosis (extreme thirst, frequent urination, confusion, or vomiting)

Finally, in the fourth subgroup (ALC combination vs placebo), GI events were most frequent in both arms, followed by CNS
The reasons for this issue vary, from poor education on how to take the medication to forgetfulness
Mounjaro is a GLP-1 weight loss medication that targets GLP-1 receptors in the body to promote weight loss
EG receives grant support from NIH/NCI R37CA266853 and NIH/NHLBI R38HL172261