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These events promote inflammation, apoptosis, and fibrogenesis, driving disease progression from simple steatosis to steatohepatitis (MASH) and ultimately cirrhosis

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Abstract Background The gut microbiota plays an important role in human health, as it can affect host immunity and susceptibility to infectious diseases

Despite the structural diversity investigated, many of the reported complexes exhibit only moderate biological activity and limited cellular selectivity, and in several cases their efficacy does not surpass that of reference drugs such as cisplatin