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Serum is the most common sample type, though it yields concentrations approximately tenfold higher than plasma because BDNF stored in platelets is released during the clotting process
C.WangZ.ChoA.et al
Further, due to electrostatic attraction, negatively charged substances like DNA or viruses can also be loaded onto the positively charged microneedles to form a coating, underscoring their versatility as platforms for diverse drugs [78]
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