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GHK-Cu: The Copper Peptide Pioneer Structure and Discovery GHK-Cu (glycyl-L-histidyl-L-lysine copper) is a naturally occurring tripeptide-copper complex first isolated from human plasma in 1973
Int J Epidemiol 2016;45:1987-96
This bidirectional regulation suggests sophisticated sensing of tissue microenvironmental cues, enabling GHK-Cu to normalize MMP activity toward homeostatic levels rather than exerting uniform stimulatory or inhibitory effects
It is found naturally in human blood where it performs a number of important biological functions
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