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This peptide then acts on multiple organs and systems: Pancreas: Stimulates insulin secretion in a glucose-dependent manner, meaning it only triggers insulin release when blood sugar is elevated
These pathways included 2-oxocarboxylic acid metabolism, dicarboxylate metabolism, glycolysis/gluconeogenesis, the tricarboxylic acid cycle, and AMPK signaling, as displayed in Figure 3A
Paulson DJ, Shug AL
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