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This included 28,430 cardiovascular deaths (103 per 100,000 person-years), 83,489 nonfatal myocardial infarctions (303 per 100,000 person-years), and 24,521 nonfatal strokes (89 per 100,000 person-years), with a number needed to treat (NNT) of 55 for MACE
After using them for over a year, people lost an average of 15% to 21% body weight, per studies on semaglutide and tirzepatide published in The New England Journal of Medicine
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