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For patients without absorption disorders, high-dose oral supplements of 1,000 to 2,000 mcg daily have been shown to be comparably effective at correcting mild to moderate deficiency at lower cost and greater convenience.

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storage in a dark location or light-protective packaging may be required per the SmPC

All the doctors agreed to change to the criteria identified by the authors , the practice nurses were advised accordingly , and a follow-up collection of data was undertaken