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Thus, long-term use of SGLT-2is may reduce the effect of weight loss

GLP-1 may impact IBD through several mechanisms, including the modulation of T-cell maturation and activity, adjustment of innate immune cell populations, like macrophages and DCs, suppression of inflammatory cytokines generation, and enhancement of tissue repair in damaged epithelium [220]

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Its proprietary strains RSB11 , RSB12 and RSB13 were developed from NIH-funded microbiome research and their formulas have been validated in clinical studies