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It plays a key role in glucose and appetite regulation by: Stimulating insulin release (glucose-dependent) Suppressing glucagon secretion Slowing gastric emptying Increasing satiety and reducing appetite In people with type 2 diabetes, this GLP-1 response is impaired leading to poor glycemic control
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Safety, Eligibility, and Who Should Consider This Approach Tirzepatide itself carries established safety monitoring: nausea, gastrointestinal side effects, and rare but serious risks like pancreatitis or thyroid concerns require provider oversight
2025;24(4):e70192
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