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The honest boundaries: these trials studied specific, supervised patient populations with clinical monitoring

I am an endocrinologist by training and spent 20 years researching diabetes and obesity at Indiana University while also seeing patients

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These effects are generally mild and often occur during the early stages of treatment while the body adjusts to the medication

JAMA points out that "these adverse events, although rare, must be considered by patients who are thinking about using the drugs for weight loss because the risk-benefit calculus for this group might differ from that of those who use them for diabetes" [20]