The question is whether it preserves useful tissue in a way that changes outcomes people actually feel : strength, mobility, fatigue, glucose handling, weight maintenance, frailty risk, and quality of life
Ondansetron may be considered, though patients should be aware of potential side effects including constipation and, rarely, QT interval prolongation

Continuous Glucose Monitoring in People at High Risk of Diabetes and Dysglycaemia: Transforming Early Risk Detection and Personalised Care Our latest review explores how continuous glucose monitoring (CGM) could transform early detection and personalised management of diabetes risk Key Highlights: CGM reveals subtle patterns of dysglycaemia in high-risk individuals, including those with pre-symptomatic type 1 diabetes with positive islet autoantibodies, pre-type 2 diabetes or other metabolic dysfunction associated with changes in body composition, metabolic dysfunction-associated steatotic liver disease, gestational diabetes mellitus, solid organ transplantation, steroid treatment CGM-derived data are not yet validated for diabetes diagnosis, and challenges remain including limited evidence, lack of consensus on abnormal CGM values in people without diabetes, and uncertainty about optimal follow-up and management
Practice Committee of the American Society for Reproductive Medicine
Nat Med 2000