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However, increased activity may expose underlying spinal issues that were previously unnoticed, especially if someone already has: disc bulges herniated discs degenerative disc disease Not all back pain is disc related, but certain symptoms may suggest nerve pressure or disc involvement

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However, compared to wild-type PNPLA3 , effects of the G-allele on the risk of LRD were significantly attenuated in those with higher consumption (top quartile) of coffee/tea (sHR: 0.06, 95% CI: 0.007-0.55) and MUFAs (sHR: 0.5, 95% CI: 0.1-0.9)