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This anion then quickly breaks a disulfide bond (Cys58 - Cys63) and leads to Cys63's nucleophilically attacking the nearest sulfide unit in the GSSG molecule (promoted by His467), which creates a mixed disulfide bond (GS-Cys58) and a GS-anion
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The intranasal spray presentation enables researchers to investigate formulation stability, analytical reproducibility, peptide integrity, and standardized delivery system performance under controlled laboratory conditions
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doi: 10.1080/15548627.2023.2196876 165 ZhuX-XMengX-YZhangAZhaoC-YChangCChenT-Xet al
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Adaptive antioxidant nanomedicines inhibit ferroptosis in renal tubular epithelial cells to alleviate diabetic kidney disease
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