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Activation of this circuit in obese mice reduces food intake and improves glucose tolerance by stimulating insulin secretion via inhibition of GABA-input-dependent sympathetic nervous activity in the paraventricular hypothalamus
Patience and adherence to the prescribed dosing schedule are crucial
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22.2 min, 100% B, all at a flow rate of 150 l min 1 , followed by 22.7 min, 100% B
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