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Patients should seek medical advice promptly if they develop severe abdominal pain, persistent vomiting, signs of dehydration or unusual weakness

First, there must be a clear scientific rationale: why this target, why this compound, and why it could potentially benefit that type of patients

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Emergency Situations (Conditions for which you would phone urgently for an ambulance.) Examples: An obviously broken ankle where the bone has pierced the skin and the person is in severe pain or shock, or a painful, swollen throat that is leading to suffocation

Fatigue or irregular heartbeat