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Mar 15 2018;186:37-44
Examples of other 3D culture systems include RPTEC/TERT1 and Nki-2 cells that, when cultured in Matrigel or Matrigel mixed with collagen I, respectively, were able to further mature and form tubular structures as seen in vivo
Skin benefits : Reduces fine lines and wrinkles Improves skin thickness Enhances firmness and elasticity Evens skin tone Reduces hyperpigmentation Promotes healing of scars and damage Improves texture Mechanisms : Stimulates collagen I and III production Promotes elastin synthesis Enhances hyaluronic acid Improves blood flow to skin Antioxidant protection Protocol : Topical : Apply serum/cream 2x daily Injectable : 1-2mg daily subcutaneous Expected results : Visible improvement in 8-12 weeks, significant changes by 6 months
For most users, once-daily evening application delivers optimal results without the downsides of aggressive protocols
Its quite tolerable, and most report it as virtually painless
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