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The Dose-Response Purity Relationship Here is a practical illustration of why purity matters in quantitative experiments: Scenario A: 98% pure IGF-1 LR3 stock (1 mg/mL) At a nominal concentration of 100 ng/mL in assay, actual IGF-1 LR3 = ~98 ng/mL Remaining ~2 ng/mL consists of low-activity or inactive related species Dose-response data is accurate
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Zafardoust S, Kazemnejad S, Darzi M, Fathi-Kazerooni M, Rastegari H, Mohammadzadeh A
Imerslund-Grsbeck syndrome in a 15-year-old German girl caused by compound heterozygous mutations in CUBN
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