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This multi-agonist strategy has potential to become the most effective pharmacological approach to reversing obesity and related metabolic disorders [32, 25]
It was originally discovered by Japanese drugmaker Chugai Pharmaceutical and licensed to Lilly in 2018
Unlike older medications that focused on just one hormone, tirzepatide injections target both, making it a more comprehensive treatment
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When the ambient temperature increases or local heat dissipation is impaired, scrotal blood flow and sweating may increase to help maintain an appropriate testicular temperature and preserve spermatogenesis (Samir et al., 2023)
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