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PCBP1 is specific to mammals, while genes orthologous to those of PCBP2, 3, and 4 are present in vertebrates, flies, and worms, and distantly related orthologs are present in yeast

Therefore, as TAX6/Calcineurin activity is calciumdependent, calcium may provide the negative feedback required for the TAX6mediated adaptation

Aoyama K, Nakaki T

That said, the profound anti-bacterial properties of these peptides deserve dedicated recognition