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Dunnetts post-hoc tests were performed for specifically comparing agonist responses with exendin-4, and Tukeys for differences between all groups
Used alone or in combination with one or more antidiabetic agents (e.g., metformin, sulfonylureas, thiazolidinediones, sodium-glucose cotransporter 2 [SGLT2] inhibitors, insulin) to improve glycemic control in patients with type 2 diabetes mellitus
An analysis of two tirzepatide trials found that plateaus typically set in somewhere between 24 and 36 weeks, depending on a persons starting weight
Stability: each peptide can be stored and handled appropriately
The standard Zepbound initiation involves starting at 2.5 mg once weekly, with increases of 2.5 mg every four weeks as tolerated, up to a maximum maintenance dose of 15 mg weekly
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