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This angiotensin IV derivative was marketed as seven orders of magnitude more potent than BDNF based on rodent studies

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Although this finding was consistent with the perspective that cell-autonomous HIF1a in Tbr2 + INPs caused oxidative stress among neural progenitors, HIF1a is also normally present in multiple cell types throughout the SGZ where it acts as a pro-neurogenesis signal among early neuroprogenitors 48,61

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