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mtROS and oxidized mtDNA serve as potent triggers of the NLRP3 inflammasome, leading to caspase-1 activation and IL-1 secretion ( Leishmania spp
This delayed gastric emptying means food remains in the stomach longer than usual, increasing the likelihood of gastrointestinal discomfort when consuming foods that are difficult to digest or that stimulate excessive gastric acid production
The resulting modified peptide may bind to receptors differently or not at all
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