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When GLP-1 medications have slowed everything down, targeted movement can help restart the engine

All real-time PCRs were performed three times and all changes in gene expression were reported as multiples of increases relative to the control while GAPDH was used as an internal control and relative gene expression between the experimental groups were determined using MxPro software

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Taken together, current evidence indicates that while a definitive causal relationship between GLP-1 RA therapy and severe motility disorders has not been established, clinicians should remain vigilant for GI symptoms suggestive of delayed gastric emptying or obstruction

For clinicians, tirzepatide remains the evidence-based choice for current patient care