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The authors would like to acknowledge the research team in the Department of Tissue Engineering and Regenerative Medicine (DTERM), Faculty of Medicine, Universiti Kebangsaan Malaysia, for the technical support throughout this review
Causes of Mitochondrial Damage Aging and oxidative damage Toxic metals lead 5 , mercury 6 , arsenic 7 Infections viral and bacterial Mold and mycotoxins 8 Industrial and agricultural toxins 9 Prescription drugs Tylenol, aspirin, anti-depressants, L-dopa, NSAIDS, statins, valproic acid, fluoroquinolones, and some chemotherapy drugs 10 Alcohol 11 DNA Adducts in Chronic Disease DNA adducts form when chemical compounds bind to DNA gene regions
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