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This "dual agonist" mimics the gut peptides glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)
In this review, the GLP-1/GLP-1R system implicated in diabetic endothelial dysfunction and related autophagy mechanism underlying the pathogenesis of diabetic vascular complications are briefly presented
Reduced appetite often leads to reduced hydration, which decreases saliva and increases dental risks
However, exceeding recommended doses significantly increases the risk of severe gastrointestinal symptoms, dehydration, electrolyte disturbances, and potentially life-threatening complications
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