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Weight Loss: For weight management, semaglutide has been tested in various trials, including the STEP (Semaglutide Treatment Effect in People with obesity) program
This concept acknowledges that semaglutide is a very long-acting medication, and its effects, including side effects, can take several weeks to fully manifest
Dehydration is the number one contributor to constipation on semaglutide
From its initial use in the treatment of type 2 diabetes to its expansion to 12 indications such as obesity, cardiovascular disease, chronic kidney disease, and metabolic dysfunction related fatty liver disease (MASLD), the annual sales of GLP-1 drugs exceeded 100 billion dollars, and its research and development funding reached a historical peak of 21.72 million dollars in 2025
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