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The origin of autophagosomes in the cell has not been well established
The only differences are dose (Wegovy goes up to 2.4 mg, Ozempic to 2.0 mg) and FDA-approved indication (Wegovy for obesity, Ozempic for diabetes)
2023;30(11):1806-1815.[DOI] 82
In OA, contrast-enhanced MRI, ultrasound-based assessment of synovitis, and synovial fluid or serum biomarkers of fibrosis and inflammation could be leveraged to directly assess changes in synovial fibro-inflammatory pathology
In clinical trials, roughly 13.6% of semaglutide participants didn't achieve 5% weight loss after 68 weeks at the highest dose, while tirzepatide non-response rates were 9-11%
