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Semaglutide's potent appetite-suppression effect makes significant weight loss achievable for many patients, which then amplifies lipid improvements beyond what the medication alone would produce
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Supplements and vitamins Most people do best with a nutrient-dense diet rather than auto-supplementing. Supplements may be considered if you are at risk of deficiency (for example vitamin D, calcium, or a multivitamin), but you should decide with your clinician
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Ideally, the findings of the above animal experiments require validation in clinical settings, to determine whether metformin can be applied to treat OA in humans
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