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This selenium-containing homotetramer protein has substrate specificity for H 2 O 2 and has been classically believed to be the major H 2 O 2 reducing enzyme
Moreover, administration of Exendin-4, a GLP-1 agonist, resulted in induction of expression of genes encoding multiple cytokines and chemokines responsible for immune response (Yusta et al
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Next-Generation Multi-Agonist Peptides The progression from GLP-1 mono-agonists (semaglutide, liraglutide) to GLP-1/GIP dual agonists (tirzepatide) to triple agonists (retatrutide: GLP-1/GIP/glucagon, Lilly Phase 3) represents a systematic intensification of multi-receptor engagement to drive superior metabolic outcomes
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