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doi:10.1002/advs.202300880
Injection Day 1 served as both the acute test and the first time point in the repeated-treatment timeline allowing evaluation of acute effects without requiring a separate acute-only experiment, minimizing animal use while preserving statistical power
67 It is, however, intriguing to observe that in gut pathologies, especially related to the colon and including chronic inflammatory conditions, claudin-1 protein expression is markedly upregulated (and mislocalized)
Flushing occurs in about 21% of users, headache in 12%
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