The search included combinations of the following terms: tirzepatide, GIP receptor agonist, GLP-1 receptor agonist, gut microbiota, obesity, metabolites, inflammation, and host metabolism. Additional relevant articles were identified through manual screening of reference lists from selected publications
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By targeting two gut hormones, tirzepatide often produces greater average weight loss than semaglutide for many patients
Association of tirzepatide with erectile dysfunction in people with type 2 diabetes