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Mitochondrial dysfunction and oxidative stress constitute central mechanisms in MASH pathogenesis, with MASLD progression closely linked to mitochondrial impairment (69)

There are two primary reasons for this

For those who are not getting blood work done regularly, he suggests either: Taking 600 mg every other day or Taking 600 mg 3 times per week, such as Monday, Wednesday, Friday Then for those who are measuring their blood regularly, a more aggressive regimen can be: 600 mg daily for a month, and then take 1 2 weeks off Gillett says that the caution in taking it daily, without any breaks, stems from a rat study that found on higher doses there was disruption to liver and kidney enzymes 9 Mode of cellular toxicity of aqueous extract of Fadogia agrestis (Schweinf

I've often posted saying it drip of B12 might be better ...who knows

Folic acid is NOT a substitute and is often ineffective or can worsen symptoms