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It signals cells to increase production of collagen, elastin, and antioxidant enzymes while suppressing certain inflammatory and tissue-destructive pathways
Nature 288(5792):715717
Primary keratinocyte culture is limited by their variability in culture conditions, and their susceptibility to irritants varies with the number of passages
J.HsuM.RajagopalanS.KaurD.RaneA.et al (2007)
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