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This is one of the most distinctive features of phentermine compared to GLP-1 medications, which build gradually over weeks
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A weight loss of 12 pounds per week is considered safe and sustainable, though initial losses may be more rapid due to fluid shifts and reduced caloric intake
The maintenance dose of semaglutide is typically between 1 mg to 2 mg once weekly, but it may vary according to the individual's response and treatment goals
Lancet 392(10148):637649 Wadden TA, Bailey TS, Billings LK, Davies M, Frias JP, Koroleva A et al (2021) Effect of subcutaneous semaglutide vs placebo as an adjunct to intensive behavioral therapy on body weight in adults with overweight or obesity: the STEP 3 randomized clinical trial
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