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Retatrutide wins on the dimensions that matter most for frontier research: higher observed ceiling in TRIUMPH-4, triple-agonist mechanism breadth, and consistent direction across both published network meta-analyses
It belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) agonists
One large study published in The Journal of Clinical Psychiatry found that people with depression had 46 percent higher levels of C-reactive protein (CRP) in their blood
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