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But barriers remain
While both studies were not powered for efficacy, buntanetap (60 and 80 mg) demonstrated improvements in cognition (Alzheimers Disease Assessment Scale-Cognitive Subscale (ADAS-Cog11)) and speed (Wechsler Adult Intelligence Scale Coding (WAIS coding)) in AD patients (80 mg vs placebo ADAS-Cog11 4.4 2.04 vs 1.1 2.63
The peptide also appears to interact with pain signaling pathways in the central nervous system, offering relief from both inflammatory and non-inflammatory pain
Parmigiani, E
Toxicol Appl Pharmacol 104:1724
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