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659 The level of GPX4 in the brain gradually decreases after TBI, and overexpression of GPX4 can partially reverse TBI-induced hippocampal ferroptosis and synaptic damage, effectively alleviating neuronal dysfunction after cerebral hemorrhage, and improving TBI-induced cognitive deficits

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Plasmid and inhibitor injection The GSTM2 overexpression or control plasmid (200 g) was mixed with HiGene I (14.4 L) (#C1507, Applygen Technologies Inc., Beijing, China)