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The association of the variant GPX4 genotypes with the increased risk of CS in hypertensives remained statistically significant after adjusting for confounding variables such as sex, body mass index (BMI), blood pressure and antihypertensive medication use (OR=2.18, 95%CI 1.463.27, P =0.0015)
Yet, analysis of data from NHANES 2003-2018, a US national cross-sectional survey of 39,438 adults, found an inverse association between selenium intake and stroke, with daily intakes of 105 g/day linked to the lowest stroke risk (93)
MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: A randomised placebo-controlled trial
Lutz T.A
