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Most patients find that any burning sensation has completely resolved within five minutes of completing the injection

There is also a separate safety question, distinct from efficacy: retatrutide raises resting heart rate by 5 to 10 beats per minute, which has not yet been characterised in patients who already have heart failure or irregular heartbeats

The biggest challenge with this specific nutrient is bioavailability

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doi:10.1016/j.urology.2013.08.039