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Because its a water-soluble vitamin, any excess that isnt used should be flushed from the body and not pose too much risk (not the case with fat-soluble vitamins like vitamin A)
Some studies suggest the quinolinium structure is sufficiently NNMT-selective that it should not broadly deplete SAM, but the wider metabolic picture remains an active research consideration
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Brain function Low levels of vitamin B12 have been linked to a decline in brain function
Furthermore, 5-Amino-1MQ remains a relevant material within research programs focused on compound characterization and analytical investigation
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