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5-Amino-1MQ works by selectively inhibiting the enzyme Nicotinamide N-methyltransferase (NNMT)

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Serum B12 reference ranges vary between laboratories, but generally, levels below 148 pmol/L are considered deficient, whilst levels between 148258 pmol/L are regarded as borderline and may warrant further investigation or a trial of treatment, particularly if symptoms are present

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Safety and evidence level: what is and isnt known In the mouse obesity study, systemic administration of the NNMT inhibitor reduced body weight, white-adipose mass and plasma cholesterol without changing food intake and without any observable adverse effects over the study period