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The most recent estimates are from 2016

Less Common but Serious Side Effects Rare but serious risks may include: Gallbladder problems Pancreatitis Severe dehydration Low blood sugar (when combined with other diabetes medications) Medical supervision significantly reduces these risks

Vitamin C Strengthens the immune system, supports collagen production, aids iron absorption, and acts as a potent antioxidant

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This combination led to a significant decrease in fasting plasma glucose levels, averaging a drop of 3.3 mmol/L