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As with any supplement, keep an eye out for any unusual reactions, but Pycnogenols long track record in adults for other uses (like decades of use for vein health) is reassuring for its safety in general
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10.1111/j.1524-4741.2009.00855.x 54 InzucchiS
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Strategic dietary modifications can significantly reduce the severity and frequency of these symptoms
However, it is believed that R-ALA -- due to its superior bioavailability -- may achieve the same benefits as ALA but at a smaller dosage
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