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Small mechanistic studies hint at additive benefits when GLP-1RA are paired with SGLT2i or non-steroidal mineralocorticoid-receptor antagonists

These are all categories that are growing quickly in both Europe and North America

Semaglutides effects on alcohol consumption appears larger than other existing FDA-approved medications for alcohol use. Questions remaining This was only a phase II trial with a relatively small sample size, so more data is needed to verify these findings and better understand the potential of GLP-1 therapy as a treatment for substance use disorders

People see Ozempic's results, hear that retatrutide produced even larger reductions in trials, and assume combining them compounds the effect

GLP-1 medications are best known for helping people manage diabetes and lose weight