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Medication Effects: SGLT2 inhibitors (such as empagliflozin, dapagliflozin, canagliflozin) commonly cause increased urination and genital/urinary tract infections as direct pharmacological effects
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No controlled studies have established causation
We chose a fixed-effects model when heterogeneity was low
The concern is indirect: most reported acute kidney injury events occurred in patients who had experienced nausea, vomiting, or diarrhea, leading to volume depletion
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