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While semaglutide does not typically affect thyroid hormones, baseline thyroid assessment is prudent given the boxed warning

My body needed the GLP-1 and clinical support, the tennis legend says in a statement

In STEP 1-3 trials of semaglutide, GI adverse effects were reported by approximately 63-83% and 34-63% in subjects randomized to OW semaglutide and placebo, respectively [11-13]

A 2025 study published in Basic & Clinical Pharmacology & Toxicology examined 32 pregnancies exposed to semaglutide alongside insulin

Ozempic, which is a brand name for semaglutide, works by mimicking a protein in your body called glucagon-like peptide 1 (GLP-1), explains Kunal Shah, MD, an assistant professor in the division of endocrinology at the Rutgers Robert Wood Johnson Medical Center