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doi: 10.1056/NEJMoa1800256 3 DruckerDJ
How oral GLP-1s compare to injectable GLP-1s 1) Convenience is different than it sounds On an empty stomach With a small amount of water Then you wait before eating, drinking, or taking other oral medications 2) Efficacy: what the data shows Weekly injectable semaglutide for weight management produced average weight loss around the mid-teens percentage range over about 68 weeks
As for cardiometabolic reversal, thats also rapid
STEP-1 showed semaglutide produced 15% at 68 weeks
Weeks 5 through 8 increase to 5 mg per week
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