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KPV, a tripeptide derived from -MSH, exhibits strong anti-inflammatory effects by downregulating pro-inflammatory cytokines and promoting immune balance, particularly in gut and epithelial tissues

Dopamine (DA) auto-oxidation is also regulated by intracellular redox state (Figure 4B), and an accumulation of oxidative dopamine metabolites leads to mitochondrial membrane depolarization, decreased ETC activity and impaired ATP synthesis (374)